By Ronald Fessenden, MD, MPHPresented at the 1st International Symposium on Honey and Human Health, January 8, 2008, in Sacramento, Calif.
Most Promising Categories of Research:
? Restorative Sleep
? Memory & Off-line Processing
? Insulin Resistance & Blood Sugar Control
? Immune System Enhancement
? Anti-microbial Effects
Types of Research Needed:
? Human Observational Studies (short term)
? Studies investigating mechanisms of action
? Clinical trials
? Population or Epidemiological Studies*
* Expensive, confounding variables, control cohorts, accidental correlations
Examples of Human Studies:
? Sleep lab studies observing REM sleep / measuring cognitive abilities post-honey dosing vs. no pre-bedtime or other food ingestion
? Expansion of oral honey ?tolerance? tests measuring effects on blood glucose, HA1c, triglycerides, HDL cholesterol, and insulin response compared to glucose, HFCS, artificial sweeteners
? Clinical trials in pre-diabetic, diabetic patients
? Mechanisms of immune system enhancement
Example of New Product:
? Honey nebulizer for prevention and inhalation treatment of tuberculosis, Valley Fever, and other antibiotic-resistant pulmonary infections
? As of January 6, 2008, provisional patents were pending in 3 countries for use of honey in a nebulizer apparatus for such use
? Clinical trials to establish efficacy and treatment protocols will be needed
Conclusions:
? The scientific and medical community should be able to deduce longer term consequences of consuming honey pending the need for population or epidemiological studies
? The potential public health benefit on metabolic diseases such as obesity, childhood obesity, insulin resistance, type II diabetes, cardiovascular disease, and neuro-degenerative diseases could be enormous
? Two years of focused research could have a significant impact on the health of the next generation



